EVALUASI KESERAGAMAN BOBOT PARASETAMOL SEDIAAN PULVERES SECARA VISUAL DI APOTEK KOTA MEDAN TAHUN 2019

Pasaribu, Jonnius (2019) EVALUASI KESERAGAMAN BOBOT PARASETAMOL SEDIAAN PULVERES SECARA VISUAL DI APOTEK KOTA MEDAN TAHUN 2019. Undergraduate thesis, Institut Kesehatan Helvetia.

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Abstract

Requests for pulverizes (still divided powder) preparations are still being done extensively by doctors both doctors in hospitals, clinics or private practices in the city of Medan. The distribution of pulverizes which is done visually (invisible) is likely to produce heterogeneity of weight, causing no dosage uniformity of the pulverise. The purpose of this study was to determine the uniformity of the weight of the pulveres preparation in paracetamol which was formulated by a Pharmacy in the City of Medan in accordance with the rules of FI edition III.
This type of research was experimental research. The research was conducted in March - June 2019. The sample of this research was paracetamol preparations of pulverizes which were formulated by 21 pharmacies from 21 sub-districts in Medan. Evaluations carried out include weight uniformity test and pulverizes weight deviation test.
The results showed that all pharmacies have large deviations or equal to 15%. All pharmacies have large deviations or equal to 15% more than two packs.
From the results of tests conducted on pulverise preparations, it can be concluded that 100% (21 pharmacies) do not meet the requirements of FI III. In further research it is advisable to make observations and evaluations related to the pulverise compounding process in Medan City pharmacy and examine the pharmacological effects that result if the pulverise produced do not meet the specified FI III requirements.
Keywords: Pharmacy, Pulveres, Weight Uniformity

Item Type: Doktoral (Undergraduate)
Additional Information: Apotek, Pulveres, Keseragaman Bobot
Subjects: Fakultas Farmasi dan Kesehatan > Farmasi > Formularium
Divisions: Fakultas Farmasi dan Kesehatan > S1 Farmasi
Depositing User: Jonnius - Pasaribu
Date Deposited: 26 Feb 2020 08:58
Last Modified: 26 Feb 2020 08:58
URI: http://repository.helvetia.ac.id/id/eprint/2348

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