HUTAHEAN, EDIRNAWATI ROULITA (2018) FORMULASI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN SINGKONG (MANIHOT ESCULENTA CRANTZ). Diploma thesis, Institut Kesehatan Helvetia.
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Abstract
Cassava (Manihot Esculenta Crantz) has antibacterial properties. The chemical content contained in cassava leaves is flavonoids, saponins and tannins. Based on the compounds owned by cassava leaves can be used to make practical and convenient form for use in hand sanitizer gel dosage forms. This study aims to formulate ethanol extract of cassava leaves in the form of hand sanitizer gel dosage form and determine the type of gel base that produces gel preparations with good physical properties.
This study used an experimental method using 10% cassava leaves extract. The ethanol extract of cassava leaves was made into gel form based on CMC-Na, HPMC, Carbopol. Evaluation of gel form which include organoleptic test, pH test, homogeneity test, dispersion test and acceptability test.
The results of the research showed that the cassava leaves (Manihot Esculenta Crantz) hand sanitizer gel form met the parameters of the physical properties of the gel, namely organoleptic test. The pH test which was still in a safe interval was among 4.5-6.5. The homogeneity test in the absence of coarse granules on all gel formulas. Acceptability test showed that the gel with CMC-Na base was preferably by respondent because it was not causing sensations such as itching, redness and swelling.
The conclusion of this study shows that cassava leaves ethanol extract (Manihot Esculenta Crantz) can be formulated in hand sanitizer gel and gel base which can produce cassava leaves ethanol extract gel with good physical properties is CMC-Na. It is suggested to the next researcher to test the antibacterial activity formulation of hand sanitizer gel form of cassava leaves (Manihot Esculenta Crantz) ethanol extract and to remove chlorophyll from cassava leaves used so that the gel produced is better.
| Item Type: | Doktoral (Diploma) |
|---|---|
| Additional Information: | Ethanol Extract of Cassava Leaves (Manihot Esculenta Crantz), Gel, Hand Sanitizer. |
| Subjects: | Fakultas Farmasi dan Kesehatan > Farmasi |
| Divisions: | Fakultas Farmasi dan Kesehatan > D3 Farmasi |
| Depositing User: | Erdinawati Hutahaean |
| Date Deposited: | 13 Dec 2018 03:08 |
| Last Modified: | 10 Mar 2020 08:21 |
| URI: | http://repository.helvetia.ac.id/id/eprint/884 |
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