Antibacterial Activity Test of Leaf Ethl Acetate Extract Distance of Fence (Jatropha curcas L.) Against Bacteria Propionibacterium Acnes and Staphylococcus Aureus

Ginting, Indra and Asriwati, Asriwati and Sari, Mayang and Tambunan, Noviyanti (2023) Antibacterial Activity Test of Leaf Ethl Acetate Extract Distance of Fence (Jatropha curcas L.) Against Bacteria Propionibacterium Acnes and Staphylococcus Aureus. International Journal Papier Advance and Scientific Review, 4 (1). 001-009. ISSN 2709-0248

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Abstract

Skin diseases are very easy to found in countries with a tropical climate. The climate that
facilitate the development of bacteria, parasites, and fungi. Acne is a skin disease that occurs
due to inflammation of the follicles polisebasea characterized by the presence of comedones,
papules, pustules and nodules. Propionibacterium acnes and Staphylococcus aureus is a
bacterium that play a role in the pathogenesis of acne that will cause inflammation. The study
was to determine the concentration of ethyl acetate extract of leaves of jatropha effectively
inhibits the growth of bacteria Propionibacterium acnes and Staphylococcus aureus. This study
was experimental research that includes plant identification, manufacture of crude dru, ethyl
acetate extract of jatropha, examination of the phytochemical screening, and test the
antibacterial activity of extracts of jatropha leaves by the method of pitting using MHA media,
the manufacture of the extract with maceration using solvent ethyl acetate. The results of
phytochemical screening of Jatropha showed the presence of flavonoid compounds, alkaloids,
saponins and tannins. The results of the antibacterial activity test showed that each
concentration had an inhibitory response that was categorized as moderate to strong on
Propionibacterium acnes bacteria with clear zone diameters of 10% (7.50mm), 20% (9.18mm),
30% (12.10mm), and 40% (15.16mm) in Staphylococcus aureus bacteria with a clear zone
diameter of 10% (8.13mm), 20% (10.21mm), 30% (12.13mm), and 40% (15.53mm). The
conclusion showed that the ethyl acetate extract of Jatropha leaves (Jatropha curcas L.) has
antibacterial activity against Propionibacterium acnes and Staphylococcus aureus.

Item Type:	Article
Uncontrolled Keywords:	Jatropha Leaves (Jatropha Curcas L.), Flavonoids, Propionibacterium Acnes, Staphylococcus Aureus
Divisions:	Fakultas Kesehatan Masyarakat
Depositing User:	Pustakawan Mr. Pustaka Helvetia
Date Deposited:	26 Oct 2023 08:20
Last Modified:	26 Oct 2023 08:20
URI:	http://repository.helvetia.ac.id/id/eprint/5546

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