Br. Sitepu, Indah Triani (2019) UJI EFEKTIVITAS SALEP EKSTRAK RIMPANG KUNYIT (Curcuma domestica Val) UNTUK PENGOBATAN LUKA SAYAT PADA TIKUS PUTIH JANTAN. Undergraduate thesis, Institut Kesehatan Helvetia.
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Abstract
Turmeric is used in various fields such as health, culinary and cosmetics. In traditional medicine, turmeric is used as an anti-inflammatory, antiseptic, anti-inflammatory, anorexia, wound medicine and liver disorders. Turmeric (Curcuma domestica Val) contains curcumin compounds which can accelerate re-epithelialization, cell proliferation, and collagen synthesis. Objective: This study aims to determine the effectiveness of turmeric rhizome extract ointment in cut wounds and to determine the comparison of the effectiveness of ointments with commercial drugs (Povidone-iodine) as treat cut. Method: This research was an experimental laboratory with a post-test control group design method. The samples used were 25 white male rats of Rattusnorvegicus aged 2-3 months which were divided into 5 groups namely povidone-iodine 10% as a positive control, ointment at a dose of 4%, 8%, turmeric rhizome extract and negative control. The treatment was carried out for 14 days. Data collection by documenting and recording the treat cut time. Result: The results showed that the 8% dose of ointment was more effective than the 4% dose in accelerating treat in white rats seen on the 8th day the wound had healed with the formation of new tissue. Whereas the 4% dose is less effective in accelerating wound healing seen in the 11th day. Conclusion: Based on the results of the study, it can be concluded that the ointment of turmeric (Curcuma domestica Val.) Extract at a dose of 8% can be used as a wounded drug but it is less effective when compared with the povidone-iodine drug.
| Item Type: | Doktoral (Undergraduate) |
|---|---|
| Uncontrolled Keywords: | Turmeric Rhizome, Ointment, Cuts, Rattus norvegicus |
| Subjects: | Fakultas Farmasi dan Kesehatan > Farmasi Fakultas Farmasi dan Kesehatan > Farmasi > Riset Farmasi |
| Divisions: | Fakultas Farmasi dan Kesehatan > S1 Farmasi |
| Depositing User: | Indah Triani Br. Sitepu |
| Date Deposited: | 26 Feb 2020 02:38 |
| Last Modified: | 26 Feb 2020 02:38 |
| URI: | http://repository.helvetia.ac.id/id/eprint/2442 |
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